Since There is no OT i'll dump the changes and my first thoughts here, if someone makes an OT feel free to use them:
Biggest Changes
You Now have to equip which items and boulders you want to use, with limited slots. Boulders take 2 slots, items take 1.
Standard Jump height is very short now, so you can no longer fly by big gaps and bypass obstacles with the default and heavier boulders.
You accelerate a lot faster and breaking is harder.
Instead of taking only the center spot and only after nullifying the terrain to build, Big aoe items need the entire AoE free to be placed, so you can no longer shield Airships with combs. In trade, placement aoe's are smaller.
Gold mines are now limited to 3 and only in specific spots.
Manual shot is now a cloud. It will spawn ~2secs after you click and it will hit and slow the enemy boulder in a generous aoe.
Balance changes
Items no longer have 3 tiers of power and cost, each item is it's own thing
Cows now spawn in groups of 5, and are sticky to the ball, making them one of the best units.
Balloons now slow your boulder if you pass under them.
Big Cannons and Big bulls are now units, and the bull can ground you.
You can click and drag towers to form big walls.
Small bombs are no more, default combs are the old mediums and old larges now spawn fireworks constantly that are small aoe explosions after 2 secs.
Elephants now also shoot projectiles on top off bumping you around
Jumping now doesn't hurt your boulder as much, but falling off stage will and it's not a small amount.
New Units
Balloons are pretty much new, as their whole concept was redesigned.
Big Cannons and Big Bulls are new placeable units instead of stage hazards.
Springtraps are relatively well hidden and can bump you out of course.
DaVinci Tanks patrol in a lin and attack from the side like a shotgun. Incredibly deadly in pairs or in chokepoints with cows.
Phoenix Trees restore unusable squares from building construction.
Whales suck boulders in (like a reverse windmill)
Boulders
Default, Angel, armoured and Tar are back
Angel and Tar regain both their unique effects after a short while.
Copernicus's boulder has a small satalite around it that destroys units and buildings
Bomb boulder explodes after it is his enough.
The Wheel is incredibly fast and hits very hard but is hard to maneuver
The Ink Boulder is frail but can jet forward while turning white squares into unusable squares.
And plenty others I'm forgetting
I'm really enjoying my time with this game, specially with the new unit selection, since matches agaisnt other people and the AI will land you against all kinds of scenarios rather than the same walls/bombs/airships/mine spam of the first.
La mancha, Copernicus and the Baba Yaga stage are all amazing. Van Gogh, Scream and Hercules stages are also beautiful.