The weirdest thing about the faces is the total lack of eye reflection. Even the original trilogy on PS360 got this right; the animation in the old games looks relatively robotic by today's standards, but the eyes still have life in them.
Every single human in Andromeda has these weirdly overdefined eyes with zero lighting interacting with them. You can see everyone's irises and pupils in excruciating detail in a way you just do not see in real life, as if they're wooden orbs with details painted on. Adding better specular effects to the eyes would on its own be a massive improvement for this game, even if the animations stayed just as stiff. It's just so off-putting being able to see everyone's eyes like this.
EDIT:
This gif going around illustrates this perfectly. Just like how the relative darkness in Ashley's scene on the right sort of hides the distinction between iris and pupil, the bright lighting in the scene on the left should be blowing out some of the detail. The eyes should have shine.