161 has tons of issues. Check out Bust A Move. Sometimes it boots with perfect sound, sometimes it doesn't.
Neo Turf Masters doesn't even boot half the time without garbled graphics.
I just played Neo Turf Masters yesterday for the first time. I booted it at least twice, and both times it worked fine. Bust a Move 1 and 2 are some of my most played games and I've never had an issue with sound or graphics. Again, maybe I'm a special case. Maybe I bought a different revision of the cart or maybe one that had modifications made.
I can only remember one issue, with Aero Fighters 3, where it froze on the first level boss, but I chalked that up to a compatibility thing where I was running it in AES mode, which technically doesn't exist. I'd never had an issue running it in MVS mode, and haven't had it happen again.
I've owned this cartridge for about a year now and I've played it a lot. I don't notice any audio artifacts or disparate quality as opposed to any of my authentic MVS cartridges, Real Bout Special, RBS2, and Art of Fighting 3. My Waku Waku 7 is a bootleg, but it works fine, too, comparatively to the multicart.
I do think that if you did a test versus mame that most people wouldn't notice the difference, but if you did a blind test going though every game the multicart it would clearly be the worst option
You're saying that MAME, an emulator running on a computer, versus a multicart on my Omega, would be identical? That's some pretty inane hyperbole, quite honestly. I understand the point you are trying to make, but this is nonsense