My predictions:
Wii U:
Pats on the back for SM3DW
Wii Sports Club: Golf
Packaged Version of Wii Fit U
DK:TF
Long presentation on Mario Kart 8 (This won't be a MEGATON, but it's going to be very cool, with in game footage and explaination of some course features, GAF will be impressed and declare MK8 a day one purchase, blah blah blah).
A couple of still of some Mario Kart 8 level in Smash Bros.
That one indie game reel will be played again.
Some meager 3rd party sizzle reel will be shown which includes Watch Dogs
3DS:
Pat on the back for LoZ:ALBW
"The Miiverse on 3DS, you like?" For half the direct, then mention and apologies over Flipnote Studio 3DS
bravely default
Kirby
Some important localization (we all think MH4 or DQ VII, it will be something like Puzzles vs Dragons Z)
Finally Mario Golf 3DS news, coming in late January
The dreamland megatons:
VC getting beefed up with GBA and N64 titles on Wii U, first games to appear after Christmas. Mario 64 to be first N64 game available on Christmas Day, will be .30 only on Christmas Day, so buy your kids a Wii U for the Nostagias
SMB3 available after the direct. First crossbuy game on NNID. Further implementation of Crossbuy to happen as time rolls on, Reggie will say something like "Y'all wanted your Kid Icarus miiverse community and got it within a week, so hold your horses, this shit takes time"
One more thing moment:
Trailer of X saying Spring 2014.
Iwata says "Happy Holidays MF'ers" and drops the mic.