What makes you think this ? I didn't see anything suggesting anything like that.
Argh I don't feel like going over the clips and timestamping everything again but basically:
1- Every time the camera or Snake stares at a bright light, there is a hissing sound heard. This happens in both trailers.
2- When Snake or the camera looks at advanced technology, the screen starts to fade out and "lens-flares"-like effects appear that are unrelated to what is happening on screen. This happens in the GZ trailer.
Basically, the patient is in coma/reliving memories in Virtual Reality, and when his eyes are exposed to bright lights in the memories or when he sees advanced technology, it triggers a waking-up effect until he stops staring, probably a side-effect from his brain starting to "remember" that what he is seeing is fake when exposed to things that are similar to what is around him in the real world (advanced technology and bright laboratory lights above his table).
A bit like how you wake up if you die when you are dreaming, because surely you couldn't be dying for real.