The question you have to ask is: how much of Monster Hunter can Capcom preserve while making a new form of it more palatable to the mainstream PS4/Xbox/PC audience? I feel like even with a more straightforward control scheme a lot of the crafting/loot aspect can be repackaged in some form. I think it's fine as long as Capcom keeps providing a traditional MH game for its existing base who can then happily ignore this new western-oriented MH if they don't like it.
In any case, an MH to PS4/Xbox One/PC standards would be a big risk for Capcom, basically as risky as building a new AAA IP. But it's probably looking at how Destiny and The Division paid off for Bungie and Ubisoft respectively. Plus, doing this with MH might be slightly less risky since it's possible some existing fans might be fine with what Capcom comes up with. You never know how many might switch over, stick with traditional MH, or play both.
If Capcom just does a traditional MH that's multiplatform between Switch, PS4, Xbox, and PC, I guess it'll get a market uptick simply for being available on more platforms, but by how much is really questionable. Maybe a few more people who don't mess with handhelds will find they like MH, but it won't do Destiny numbers or whatever because most PlayStation/Xbox gamers will just find its controls and rule set weird. And that's if Capcom doesn't drastically increase the production value of the art assets and everything. I still feel like if it's Switch-only, MH will have the same PS2-era graphics, just at a higher resolution, maybe a bit better from some easily implementable things the new hardware would allow. MH with Division-level graphics though (or more appropriately, Deep Down-level graphics) on the other consoles and PC on the other hand might necessitate appealing to the mainstream market.
The thing is though they didn't give a damn about the RE vets when they went with RE4 and when they went this new one. Why would they care what a small percent of the MH vets care about? I'm sure the bulk of the fanbase just wants to dress their characters and palicoes in bad ass armor while playing online with their buds. The people calculating damage output and motion values are probably a niche as you can get and the only ones to actually complain about mechanic changes.