That depends on how Sakurai views indie characters (as the trophies could have easily been a request of NoA). But let's be honest, who knows at this point? Surely not us.
Honestly I don't think either of those characters have much of a shot just because, well, 95% of people have no idea who they are. But Layton would definitely lower the bar from "iconic, decades-old Mount Rushmore of gaming" types considerably.
...though I can't really think of many other mid-tier characters on Layton's level that still feel "right" for Smash.