Reveal titles?
Just as a bit of fun...
3D Mario
Retro's new game
Zelda WiiU NX
Pikmin 4
A new IP or two from the Garage program
Something Splatoon- probably a spin-off rather than a sequel, to communicate the message that the franchise has a future.
A pack-in game, similar to Wii Sports or Nintendoland- possibly something incorporating Amiibo?
Smash Bros. For NX- what we got on Wii U and 3DS, with the DLC characters, stages and costumes included.
Maybe Pokémon, if Z and Go are already out by the reveal and Game Freak want to get in on the ground floor.
Monster Hunter (N)X
Yo-Kai Watch
DQ XI
FF XIV
A few smaller Japanese titles, as they try and hold on to the last remnants of the handheld market.
Skylanders, Disney Infinity, Lego Dimensions etc.
Nothing earth-shattering, sure, but I'd say this is reasonably feasible judging by Nintendo's recent development. Of course, there's no telling how the reorganisation and foundation of EPD has changed things, but I don't think there's anything too unreasonable here.